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Objective: To see the radiographic cervical spine damage in polyarticular juvenile idiopathic arthritis (PJIA) coming to a tertiary care hospital in Islamabad, Pakistan. Study Design: Cross-sectional descriptive study. Place and Duration of Study: The study was conducted in department of Rheumatology at Pakistan Institute of Medical Sciences from Jun 2013 to Dec 2013. Subjects and Methods: A total of 50 patients of PJIA coming to Rheumatology Outpatient Department were recruited in the study after informed consent. Radiographs of cervical spine were performed for each patient in antero-posterior, lateral with flexion and extension and open-mouth views. Radiographs were reviewed for the...
Background: Ghrelin is a 28-amino acid acylated peptide released from the enteroendocrine cells of stomach. Aim of the study was to find out the possible beneficial role of ghrelin in erythropoiesis of myelosuppressed rats and its possible mediator. Methods: This randomized control trial was carried out at the Department of Physiology Foundation University Medical College in collaboration with the National Institute of Health, Islamabad, from February 2013 to June 2014. A total of 130 Sprague-Dawley rats were randomly divided into four groups. Group I was treated with ghrelin only (1 nmol/100µl), group II received intraperitoneal carboplatin and 5-flurouracil (5-FU) only while group III...